Multilevel Modelling for Missing Data in Longitudinal Studies

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Multilevel Modelling for Missing Data in Longitudinal Studies

A one day workshop by Don Hedeker, University of Illinois at Chicago, to be held on Thursday 11^th November at the Postgraduate Statistics Centre, Lancaster University

Registration ¦ How to get to Lancaster University ¦ Short biography of Don Hedeker | course materials

In this 1-day workshop, attendees will learn about the use of multilevel or mixed models for analysis of missing data in longitudinal studies. The focus will be on data analysis, with direct application illustrated using standard statistical software (i.e., SAS). Some of the topics to be covered include: (1) missing data mechanisms in longitudinal studies, (2) pattern-mixture and selection models for non-ignorable missing data; also simple multiple imputation methods for non-ignorable binary outcomes will be described.

1) Missing data in longitudinal studies are common, and so methods for dealing with missing data will be discussed. First, the various missing data mechanisms (missing completely at random, missing at random, not missing at random) proposed by Rubin in the 1970s will be defined. Methods for testing the missing completely at random assumption will be illustrated for longitudinal data.

2) For situations in which the missing at random assumption does not seem tenable, sensitivity analysis will be detailed. In particular, non-ignorable pattern-mixture and selection models will be described and illustrated. Though these models can be complex, it will be shown how they can be estimated using SAS PROC NLMIXED. Finally, for dichotomous outcomes, a simple multiple imputation approach will be described for non-ignorable missing data.

Reading materials - see http://www.uic.edu/classes/bstt/bstt513/pubs.html

Hedeker, D. & Gibbons, R. D. (1997). Application of random-effects pattern-mixture models for missing data in longitudinal studies. Psychological Methods, 2, 64-78.

Hedeker, D. & Gibbons, R. D. (2006). Longitudinal Data Analysis. Wiley, New York.

Hedeker, D., Mermelstein, R.J., & Demirtas, H. (2007). Analysis of binary outcomes with missing data: missing=smoking, last observation carried forward, and a little multiple imputation. Addiction, 102, 1564-1573.

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May

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Lancaster-Warwick-Stirling node

Research Methods

Substantive areas

Tag cloud

Multilevel Modelling for Missing Data in Longitudinal Studies

A one day workshop by Don Hedeker, University of Illinois at Chicago, to be held on Thursday 11^th November at the Postgraduate Statistics Centre, Lancaster University

Registration ¦ How to get to Lancaster University ¦ Short biography of Don Hedeker | course materials

Calendar

May

Primary links

User login

Lancaster-Warwick-Stirling node

Research Methods

Substantive areas

Tag cloud

Multilevel Modelling for Missing Data in Longitudinal Studies

A one day workshop by Don Hedeker, University of Illinois at Chicago, to be held on Thursday 11th November at the Postgraduate Statistics Centre, Lancaster University

Registration ¦ How to get to Lancaster University ¦ Short biography of Don Hedeker | course materials

Calendar

May

Primary links

User login

A one day workshop by Don Hedeker, University of Illinois at Chicago, to be held on Thursday 11^th November at the Postgraduate Statistics Centre, Lancaster University